Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis.
Identifieur interne : 001E12 ( Main/Exploration ); précédent : 001E11; suivant : 001E13Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis.
Auteurs : He-Shui Wu [République populaire de Chine] ; Lei Zhang ; Yan Chen ; Xing-Jun Guo ; Lin Wang ; Jian-Bo Xu ; Chun-You Wang ; Jing-Hui ZhangSource :
- Hepatobiliary & pancreatic diseases international : HBPD INT [ 1499-3872 ] ; 2005.
Descripteurs français
- KwdFr :
- ARN messager (génétique), Amorces ADN, Animaux, Arginine (pharmacologie), Hémorragie (génétique), Hémorragie (physiopathologie), Inflammation, Monoxyde d'azote (usage thérapeutique), Mâle, Pancréatite aigüe nécrotique (génétique), Pancréatite aigüe nécrotique (physiopathologie), Poumon (), Poumon (anatomopathologie), RT-PCR, Rat Sprague-Dawley, Rats, Récepteur de type Toll-2 (génétique), Récepteur de type Toll-4 (génétique), Régulation de l'expression des gènes (), Séquence nucléotidique.
- MESH :
- anatomopathologie : Poumon.
- génétique : ARN messager, Hémorragie, Pancréatite aigüe nécrotique, Récepteur de type Toll-2, Récepteur de type Toll-4.
- pharmacologie : Arginine.
- physiopathologie : Hémorragie, Pancréatite aigüe nécrotique.
- usage thérapeutique : Monoxyde d'azote.
- Amorces ADN, Animaux, Inflammation, Mâle, Poumon, RT-PCR, Rat Sprague-Dawley, Rats, Régulation de l'expression des gènes, Séquence nucléotidique.
English descriptors
- KwdEn :
- Animals, Arginine (pharmacology), Base Sequence, DNA Primers, Gene Expression Regulation (drug effects), Hemorrhage (genetics), Hemorrhage (physiopathology), Inflammation, Lung (drug effects), Lung (pathology), Male, Nitric Oxide (therapeutic use), Pancreatitis, Acute Necrotizing (genetics), Pancreatitis, Acute Necrotizing (physiopathology), RNA, Messenger (genetics), Rats, Rats, Sprague-Dawley, Reverse Transcriptase Polymerase Chain Reaction, Toll-Like Receptor 2 (genetics), Toll-Like Receptor 4 (genetics).
- MESH :
- chemical , genetics : RNA, Messenger, Toll-Like Receptor 2, Toll-Like Receptor 4.
- chemical , pharmacology : Arginine.
- drug effects : Gene Expression Regulation, Lung.
- genetics : Hemorrhage, Pancreatitis, Acute Necrotizing.
- pathology : Lung.
- physiopathology : Hemorrhage, Pancreatitis, Acute Necrotizing.
- chemical , therapeutic use : Nitric Oxide.
- Animals, Base Sequence, DNA Primers, Inflammation, Male, Rats, Rats, Sprague-Dawley, Reverse Transcriptase Polymerase Chain Reaction.
Abstract
Toll-like receptor (TLR) 2/4 might play important roles in mediating proinflammatory cytokine synthesis and release. And nitric oxide (NO) has been used to treat acute respiratory distress syndrome (ARDS). This study aimed to investigate the changes in TLR2/4 gene expression in the lungs of rats with acute lung injury (ALI) complicated by acute hemorrhage necrotizing pancreatitis (AHNP) and the effect of NO on the TLR2/4 gene expression.
PubMed: 16286274
Affiliations:
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Le document en format XML
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acute hemorrhage necrotizing pancreatitis.</title><author><name sortKey="Wu, He Shui" sort="Wu, He Shui" uniqKey="Wu H" first="He-Shui" last="Wu">He-Shui Wu</name><affiliation wicri:level="1"><nlm:affiliation>Center of Pancreatic Surgery, Affiliated Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Center of Pancreatic Surgery, Affiliated Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Zhang, Lei" sort="Zhang, Lei" uniqKey="Zhang L" first="Lei" last="Zhang">Lei Zhang</name></author><author><name sortKey="Chen, Yan" sort="Chen, Yan" uniqKey="Chen Y" first="Yan" last="Chen">Yan Chen</name></author><author><name sortKey="Guo, Xing Jun" sort="Guo, Xing Jun" uniqKey="Guo X" first="Xing-Jun" last="Guo">Xing-Jun Guo</name></author><author><name sortKey="Wang, Lin" sort="Wang, Lin" uniqKey="Wang L" first="Lin" last="Wang">Lin Wang</name></author><author><name sortKey="Xu, Jian Bo" sort="Xu, Jian Bo" uniqKey="Xu J" first="Jian-Bo" last="Xu">Jian-Bo Xu</name></author><author><name sortKey="Wang, Chun You" sort="Wang, Chun You" uniqKey="Wang C" first="Chun-You" last="Wang">Chun-You Wang</name></author><author><name sortKey="Zhang, Jing Hui" sort="Zhang, Jing Hui" uniqKey="Zhang J" first="Jing-Hui" last="Zhang">Jing-Hui Zhang</name></author></analytic><series><title level="j">Hepatobiliary & pancreatic diseases international : HBPD INT</title><idno type="ISSN">1499-3872</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Arginine 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thérapeutique)</term><term>Mâle</term><term>Pancréatite aigüe nécrotique (génétique)</term><term>Pancréatite aigüe nécrotique (physiopathologie)</term><term>Poumon ()</term><term>Poumon (anatomopathologie)</term><term>RT-PCR</term><term>Rat Sprague-Dawley</term><term>Rats</term><term>Récepteur de type Toll-2 (génétique)</term><term>Récepteur de type Toll-4 (génétique)</term><term>Régulation de l'expression des gènes ()</term><term>Séquence nucléotidique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA, Messenger</term><term>Toll-Like Receptor 2</term><term>Toll-Like Receptor 4</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Arginine</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Poumon</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Gene Expression 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Oxide</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Monoxyde d'azote</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Base Sequence</term><term>DNA Primers</term><term>Inflammation</term><term>Male</term><term>Rats</term><term>Rats, Sprague-Dawley</term><term>Reverse Transcriptase Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Amorces ADN</term><term>Animaux</term><term>Inflammation</term><term>Mâle</term><term>Poumon</term><term>RT-PCR</term><term>Rat Sprague-Dawley</term><term>Rats</term><term>Régulation de l'expression des gènes</term><term>Séquence nucléotidique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Toll-like receptor (TLR) 2/4 might play important roles in mediating proinflammatory cytokine synthesis and release. And nitric oxide (NO) has been used to treat acute respiratory distress syndrome (ARDS). This study aimed to investigate the changes in TLR2/4 gene expression in the lungs of rats with acute lung injury (ALI) complicated by acute hemorrhage necrotizing pancreatitis (AHNP) and the effect of NO on the TLR2/4 gene expression.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Hubei</li></region><settlement><li>Wuhan</li></settlement></list><tree><noCountry><name sortKey="Chen, Yan" sort="Chen, Yan" uniqKey="Chen Y" first="Yan" last="Chen">Yan Chen</name><name sortKey="Guo, Xing Jun" sort="Guo, Xing Jun" uniqKey="Guo X" first="Xing-Jun" last="Guo">Xing-Jun Guo</name><name sortKey="Wang, Chun You" sort="Wang, Chun You" uniqKey="Wang C" first="Chun-You" last="Wang">Chun-You Wang</name><name sortKey="Wang, Lin" sort="Wang, Lin" uniqKey="Wang L" first="Lin" last="Wang">Lin Wang</name><name sortKey="Xu, Jian Bo" sort="Xu, Jian Bo" uniqKey="Xu J" first="Jian-Bo" last="Xu">Jian-Bo Xu</name><name sortKey="Zhang, Jing Hui" sort="Zhang, Jing Hui" uniqKey="Zhang J" first="Jing-Hui" last="Zhang">Jing-Hui Zhang</name><name sortKey="Zhang, Lei" sort="Zhang, Lei" uniqKey="Zhang L" first="Lei" last="Zhang">Lei Zhang</name></noCountry><country name="République populaire de Chine"><region name="Hubei"><name sortKey="Wu, He Shui" sort="Wu, He Shui" uniqKey="Wu H" first="He-Shui" last="Wu">He-Shui Wu</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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